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Proteomic Analysis of Hippocampus in a Mouse Model of Depression Reveals Neuroprotective Function of Ubiquitin C-terminal Hydrolase L1 (UCH-L1) via Stress-induced Cysteine Oxidative Modifications
Chronic physical restraint stress increases oxidative stress in the brain, and dysregulation of oxidative stress can be one of the causes of major depressive disorder. To understand the underlying mechanisms, we undertook a systematic proteomic analysis of hippocampus in a chronic restraint stress m...
Autores principales: | Choi, Jung-Eun, Lee, Jae-Jin, Kang, Wonmo, Kim, Hyun Jung, Cho, Jin-Hwan, Han, Pyung-Lim, Lee, Kong-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126396/ https://www.ncbi.nlm.nih.gov/pubmed/29959188 http://dx.doi.org/10.1074/mcp.RA118.000835 |
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