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Estimating the frequency of multiplets in single-cell RNA sequencing from cell-mixing experiments
In single-cell RNA-sequencing, it is important to know the frequency at which the sequenced transcriptomes actually derive from multiple cells. A common method to estimate this multiplet frequency is to mix two different types of cells (e.g., human and mouse), and then determine how often the transc...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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PeerJ Inc.
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126471/ https://www.ncbi.nlm.nih.gov/pubmed/30202659 http://dx.doi.org/10.7717/peerj.5578 |