Purification of Cyclic GMP-AMP from Viruses and Measurement of Its Activity in Cell Culture

Sensing of cytoplasmic DNA by cGAS is essential for the initiation of immune responses against several viruses. cGAS also plays important roles in some autoinflammatory and autoimmune diseases and may be involved in immune responses targeting cancer cells. Once activated, cGAS catalyzes the formatio...

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Detalles Bibliográficos
Autores principales: Mayer, Alice, Maelfait, Jonathan, Bridgeman, Anne, Rehwinkel, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer New York 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126575/
https://www.ncbi.nlm.nih.gov/pubmed/28808967
http://dx.doi.org/10.1007/978-1-4939-7237-1_8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126575/
https://www.ncbi.nlm.nih.gov/pubmed/28808967
http://dx.doi.org/10.1007/978-1-4939-7237-1_8

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