Twist and turn: a revised structural view on the unpaired bubble of class II CPD photolyase in complex with damaged DNA

Cyclobutane pyrimidine dimer (CPD) photolyases harness the energy of blue light to repair UV-induced DNA CPDs. Upon binding, CPD photolyases cause the photodamage to flip out of the duplex DNA and into the catalytic site of the enzyme. This process, called base-flipping, induces a kink in the DNA, a...

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Detalles Bibliográficos
Autores principales: Maestre-Reyna, Manuel, Yamamoto, Junpei, Huang, Wei-Cheng, Tsai, Ming-Daw, Essen, Lars-Oliver, Bessho, Yoshitaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2018
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126647/
https://www.ncbi.nlm.nih.gov/pubmed/30224964
http://dx.doi.org/10.1107/S205225251800996X

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126647/
https://www.ncbi.nlm.nih.gov/pubmed/30224964
http://dx.doi.org/10.1107/S205225251800996X

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