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SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma

SPIN1 is necessary for normal meiotic progression in mammals. It is overexpressed in human ovarian cancers and some cancer cell lines. Here, we examined the functional significance and regulation of SPIN1 and SPIN3 in the TCam-2 human seminoma cell line. We found that while SPIN1 overexpression redu...

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Detalles Bibliográficos
Autores principales: Janecki, Damian Mikolaj, Sajek, Marcin, Smialek, Maciej Jerzy, Kotecki, Maciej, Ginter-Matuszewska, Barbara, Kuczynska, Bogna, Spik, Anna, Kolanowski, Tomasz, Kitazawa, Riko, Kurpisz, Maciej, Jaruzelska, Jadwiga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126697/
https://www.ncbi.nlm.nih.gov/pubmed/30197756
http://dx.doi.org/10.18632/oncotarget.25977