Cargando…
SPIN1 is a proto-oncogene and SPIN3 is a tumor suppressor in human seminoma
SPIN1 is necessary for normal meiotic progression in mammals. It is overexpressed in human ovarian cancers and some cancer cell lines. Here, we examined the functional significance and regulation of SPIN1 and SPIN3 in the TCam-2 human seminoma cell line. We found that while SPIN1 overexpression redu...
Autores principales: | Janecki, Damian Mikolaj, Sajek, Marcin, Smialek, Maciej Jerzy, Kotecki, Maciej, Ginter-Matuszewska, Barbara, Kuczynska, Bogna, Spik, Anna, Kolanowski, Tomasz, Kitazawa, Riko, Kurpisz, Maciej, Jaruzelska, Jadwiga |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126697/ https://www.ncbi.nlm.nih.gov/pubmed/30197756 http://dx.doi.org/10.18632/oncotarget.25977 |
Ejemplares similares
-
Human NANOS1 Represses Apoptosis by Downregulating Pro-Apoptotic Genes in the Male Germ Cell Line
por: Janecki, Damian M., et al.
Publicado: (2020) -
Characterization of RNP Networks of PUM1 and PUM2 Post-Transcriptional Regulators in TCam-2 Cells, a Human Male Germ Cell Model
por: Smialek, Maciej J., et al.
Publicado: (2020) -
Distinct Roles of NANOS1 and NANOS3 in the Cell Cycle and NANOS3-PUM1-FOXM1 Axis to Control G2/M Phase in a Human Primordial Germ Cell Model
por: Ilaslan, Erkut, et al.
Publicado: (2022) -
Role of PUM RNA-Binding Proteins in Cancer
por: Smialek, Maciej J., et al.
Publicado: (2021) -
RNAlign2D: a rapid method for combined RNA structure and sequence-based alignment using a pseudo-amino acid substitution matrix
por: Woźniak, Tomasz, et al.
Publicado: (2021)