Tyrosyl-tRNA synthetase stimulates thrombopoietin-independent hematopoiesis accelerating recovery from thrombocytopenia

New mechanisms behind blood cell formation continue to be uncovered, with therapeutic approaches for hematological diseases being of great interest. Here we report an enzyme in protein synthesis, known for cell-based activities beyond translation, is a factor inducing megakaryocyte-biased hematopoie...

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Detalles Bibliográficos
Autores principales: Kanaji, Taisuke, Vo, My-Nuong, Kanaji, Sachiko, Zarpellon, Alessandro, Shapiro, Ryan, Morodomi, Yosuke, Yuzuriha, Akinori, Eto, Koji, Belani, Rajesh, Do, Minh-Ha, Yang, Xiang-Lei, Ruggeri, Zaverio M., Schimmel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
PNAS Plus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126720/
https://www.ncbi.nlm.nih.gov/pubmed/30104364
http://dx.doi.org/10.1073/pnas.1807000115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126720/
https://www.ncbi.nlm.nih.gov/pubmed/30104364
http://dx.doi.org/10.1073/pnas.1807000115

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