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Control of the Restriction Point by Rb and p21

The Restriction Point was originally defined as the moment that cells commit to the cell cycle and was later suggested to coincide with hyperphosphorylation of the retinoblastoma protein (Rb). Current cell cycle models posit that cells exit mitosis into a pre-Restriction Point state, where they have...

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Detalles Bibliográficos
Autores principales: Moser, Justin, Miller, Iain, Carter, Dylan, Spencer, Sabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126733/
https://www.ncbi.nlm.nih.gov/pubmed/30111539
http://dx.doi.org/10.1073/pnas.1722446115