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Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8
Oligodendrocyte precursor cells (OPCs) constitute the main proliferative cells in the adult brain, and deregulation of OPC proliferation-differentiation balance results in either glioma formation or defective adaptive (re)myelination. OPC differentiation requires significant genetic reprogramming, i...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126750/ https://www.ncbi.nlm.nih.gov/pubmed/30108144 http://dx.doi.org/10.1073/pnas.1802620115 |