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Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8

Oligodendrocyte precursor cells (OPCs) constitute the main proliferative cells in the adult brain, and deregulation of OPC proliferation-differentiation balance results in either glioma formation or defective adaptive (re)myelination. OPC differentiation requires significant genetic reprogramming, i...

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Detalles Bibliográficos
Autores principales: Marie, Corentine, Clavairoly, Adrien, Frah, Magali, Hmidan, Hatem, Yan, Jun, Zhao, Chuntao, Van Steenwinckel, Juliette, Daveau, Romain, Zalc, Bernard, Hassan, Bassem, Thomas, Jean-Léon, Gressens, Pierre, Ravassard, Philippe, Moszer, Ivan, Martin, Donna M., Lu, Q. Richard, Parras, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126750/
https://www.ncbi.nlm.nih.gov/pubmed/30108144
http://dx.doi.org/10.1073/pnas.1802620115