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Cellular function given parametric variation in the Hodgkin and Huxley model of excitability

How is reliable physiological function maintained in cells despite considerable variability in the values of key parameters of multiple interacting processes that govern that function? Here, we use the classic Hodgkin–Huxley formulation of the squid giant axon action potential to propose a possible...

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Detalles Bibliográficos
Autores principales: Ori, Hillel, Marder, Eve, Marom, Shimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126753/
https://www.ncbi.nlm.nih.gov/pubmed/30111538
http://dx.doi.org/10.1073/pnas.1808552115