Novel isothiacalothrixin B analogues exhibit cytotoxic activity on human colon cancer cells in vitro by inducing irreversible DNA damage

Preliminary cytotoxic analysis of sulphur containing isosteric analogues of calothrixin B identified the useful anti-tumour activity of thia/isothiacalothrixin B which necessitated it’s biological evaluation in colon and lung cancer cell lines. The isothia analogues induced cytotoxicity of HCT116 in...

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Detalles Bibliográficos
Autores principales: Dhatchana Moorthy, Nachiappan, Muthu Ramalingam, Bose, Iqbal, Saleem, Mohanakrishnan, Arasambattu K, Gunasekaran, Krishnasamy, Vellaichamy, Elangovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126808/
https://www.ncbi.nlm.nih.gov/pubmed/30188913
http://dx.doi.org/10.1371/journal.pone.0202903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126808/
https://www.ncbi.nlm.nih.gov/pubmed/30188913
http://dx.doi.org/10.1371/journal.pone.0202903

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