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(1)H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures

INTRODUCTION: Ex vivo cell expansion under Good Manufacturing Practice (GMP) guidelines can be performed using medium additives containing human growth factors from platelets. These products can differently affect proliferation of adipose mesenchymal stromal stem cells (ASC). Qualification of medium...

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Detalles Bibliográficos
Autores principales: Agostini, Francesco, Ruzza, Marta, Corpillo, Davide, Biondi, Luca, Acquadro, Elena, Canepa, Barbara, Viale, Alessandra, Battiston, Monica, Serra, Fabrizio, Aime, Silvio, Mazzucato, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126812/
https://www.ncbi.nlm.nih.gov/pubmed/30188924
http://dx.doi.org/10.1371/journal.pone.0203048