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(1)H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures
INTRODUCTION: Ex vivo cell expansion under Good Manufacturing Practice (GMP) guidelines can be performed using medium additives containing human growth factors from platelets. These products can differently affect proliferation of adipose mesenchymal stromal stem cells (ASC). Qualification of medium...
Autores principales: | Agostini, Francesco, Ruzza, Marta, Corpillo, Davide, Biondi, Luca, Acquadro, Elena, Canepa, Barbara, Viale, Alessandra, Battiston, Monica, Serra, Fabrizio, Aime, Silvio, Mazzucato, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126812/ https://www.ncbi.nlm.nih.gov/pubmed/30188924 http://dx.doi.org/10.1371/journal.pone.0203048 |
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