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Alterations of the nigrostriatal pathway in a 6-OHDA rat model of Parkinson’s disease evaluated with multimodal MRI

Parkinson’s disease is characterized by neurodegeneration of the dopaminergic neurons in the substantia nigra pars compacta. The 6-hydroxydopamine (6-OHDA) rat model has been used to study neurodegeneration in the nigro-striatal dopaminergic system. The goal of this study was to evaluate the reliabi...

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Detalles Bibliográficos
Autores principales: Perlbarg, Vincent, Lambert, Justine, Butler, Benjamin, Felfli, Mehdi, Valabrègue, Romain, Privat, Anne-Laure, Lehéricy, Stéphane, Petiet, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126820/
https://www.ncbi.nlm.nih.gov/pubmed/30188909
http://dx.doi.org/10.1371/journal.pone.0202597