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Prd1 associates with the clathrin adaptor α-Adaptin and the kinesin-3 Imac/Unc-104 to govern dendrite pruning in Drosophila

Refinement of the nervous system depends on selective removal of excessive axons/dendrites, a process known as pruning. Drosophila ddaC sensory neurons prune their larval dendrites via endo-lysosomal degradation of the L1-type cell adhesion molecule (L1-CAM), Neuroglian (Nrg). Here, we have identifi...

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Detalles Bibliográficos
Autores principales: Zong, Wenhui, Wang, Yan, Tang, Quan, Zhang, Heng, Yu, Fengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126864/
https://www.ncbi.nlm.nih.gov/pubmed/30142146
http://dx.doi.org/10.1371/journal.pbio.2004506