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coTRaCTE predicts co-occurring transcription factors within cell-type specific enhancers

Cell-type specific gene expression is regulated by the combinatorial action of transcription factors (TFs). In this study, we predict transcription factor (TF) combinations that cooperatively bind in a cell-type specific manner. We first divide DNase hypersensitive sites into cell-type specifically...

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Detalles Bibliográficos
Autores principales: van Bömmel, Alena, Love, Michael I., Chung, Ho-Ryun, Vingron, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126874/
https://www.ncbi.nlm.nih.gov/pubmed/30142147
http://dx.doi.org/10.1371/journal.pcbi.1006372