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Whi2 is a conserved negative regulator of TORC1 in response to low amino acids

Yeast WHI2 was originally identified in a genetic screen for regulators of cell cycle arrest and later suggested to function in general stress responses. However, the function of Whi2 is unknown. Whi2 has predicted structure and sequence similarity to human KCTD family proteins, which have been impl...

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Detalles Bibliográficos
Autores principales: Chen, Xianghui, Wang, Guiqin, Zhang, Yu, Dayhoff-Brannigan, Margaret, Diny, Nicola L., Zhao, Mingjun, He, Ge, Sing, Cierra N., Metz, Kyle A., Stolp, Zachary D., Aouacheria, Abdel, Cheng, Wen-Chih, Hardwick, J. Marie, Teng, Xinchen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126876/
https://www.ncbi.nlm.nih.gov/pubmed/30142151
http://dx.doi.org/10.1371/journal.pgen.1007592