Cargando…
Whi2 is a conserved negative regulator of TORC1 in response to low amino acids
Yeast WHI2 was originally identified in a genetic screen for regulators of cell cycle arrest and later suggested to function in general stress responses. However, the function of Whi2 is unknown. Whi2 has predicted structure and sequence similarity to human KCTD family proteins, which have been impl...
Autores principales: | Chen, Xianghui, Wang, Guiqin, Zhang, Yu, Dayhoff-Brannigan, Margaret, Diny, Nicola L., Zhao, Mingjun, He, Ge, Sing, Cierra N., Metz, Kyle A., Stolp, Zachary D., Aouacheria, Abdel, Cheng, Wen-Chih, Hardwick, J. Marie, Teng, Xinchen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126876/ https://www.ncbi.nlm.nih.gov/pubmed/30142151 http://dx.doi.org/10.1371/journal.pgen.1007592 |
Ejemplares similares
-
KCTD: A new gene family involved in neurodevelopmental and neuropsychiatric disorders
por: Teng, Xinchen, et al.
Publicado: (2019) -
Redefining the BH3 Death Domain as a ‘Short Linear Motif’
por: Aouacheria, Abdel, et al.
Publicado: (2015) -
Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signaling
por: Powis, Katie, et al.
Publicado: (2016) -
Evolution of Bcl-2 homology motifs: homology versus homoplasy
por: Aouacheria, Abdel, et al.
Publicado: (2013) -
Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization
por: Stolp, Zachary D., et al.
Publicado: (2022)