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xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression

Many tumors increase uptake and dependence on glucose, cystine or glutamine. These basic observations on cancer cell metabolism have opened multiple new diagnostic and therapeutic avenues in cancer research. Recent studies demonstrated that smoking could induce the expression of xCT (SLC7A11) in ora...

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Detalles Bibliográficos
Autores principales: Ji, Xiangming, Qian, Jun, Rahman, S. M. Jamshedur, Siska, Peter J., Zou, Yong, Harris, Bradford K., Hoeksema, Megan D., Trenary, Irina A., Heidi, Chen, Eisenberg, Rosana, Rathmell, Jeffrey C., Young, Jamey D., Massion, Pierre P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127081/
https://www.ncbi.nlm.nih.gov/pubmed/29789716
http://dx.doi.org/10.1038/s41388-018-0307-z