LOX-catalyzed collagen stabilization is a proximal cause for intrinsic resistance to chemotherapy

The potential of altering the tumor ECM to improve drug response remains fairly unexplored. To identify targets for modification of the ECM aiming to improve drug response and overcome resistance, we analyzed expression data sets from pre-treatment patient cohorts. Cross-evaluation identified a subs...

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Detalles Bibliográficos
Autores principales: Rossow, Leonie, Veitl, Simona, Vorlová, Sandra, Wax, Jacqueline K., Kuhn, Anja E., Maltzahn, Verena, Upcin, Berin, Karl, Franziska, Hoffmann, Helene, Gätzner, Sabine, Kallius, Matthias, Nandigama, Rajender, Scheld, Daniela, Irmak, Ster, Herterich, Sabine, Zernecke, Alma, Ergün, Süleyman, Henke, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127085/
https://www.ncbi.nlm.nih.gov/pubmed/29780168
http://dx.doi.org/10.1038/s41388-018-0320-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127085/
https://www.ncbi.nlm.nih.gov/pubmed/29780168
http://dx.doi.org/10.1038/s41388-018-0320-2

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