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microCLIP super learning framework uncovers functional transcriptome-wide miRNA interactions

Argonaute crosslinking and immunoprecipitation (CLIP) experiments are the most widely used high-throughput methodologies for miRNA targetome characterization. The analysis of Photoactivatable Ribonucleoside-Enhanced (PAR) CLIP methodology focuses on sequence clusters containing T-to-C conversions. H...

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Detalles Bibliográficos
Autores principales: Paraskevopoulou, Maria D., Karagkouni, Dimitra, Vlachos, Ioannis S., Tastsoglou, Spyros, Hatzigeorgiou, Artemis G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127135/
https://www.ncbi.nlm.nih.gov/pubmed/30190538
http://dx.doi.org/10.1038/s41467-018-06046-y