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Imidazole Compounds for Protecting Choroidal Endothelial Cells from Complement Injury

Age-related macular degeneration (AMD) is a common, blinding disease associated with increased complement system activity. Eyes with AMD show elevated accumulation of the membrane attack complex (MAC) in the choriocapillaris and degeneration of macular choriocapillaris endothelial cells (ECs). Thus,...

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Detalles Bibliográficos
Autores principales: Zeng, Shemin, Wen, Kuo-Kuang, Workalemahu, Grefachew, Sohn, Elliott H., Wu, Meng, Chirco, Kathleen R., Flamme-Wiese, Miles J., Liu, Xiuying, Stone, Edwin M., Tucker, Budd A., Mullins, Robert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127142/
https://www.ncbi.nlm.nih.gov/pubmed/30190604
http://dx.doi.org/10.1038/s41598-018-31846-z