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Structure of the human plasma membrane Ca(2+)-ATPase 1 in complex with its obligatory subunit neuroplastin

Plasma membrane Ca(2+)-ATPases (PMCAs) are key regulators of global Ca(2+) homeostasis and local intracellular Ca(2+) dynamics. Recently, Neuroplastin (NPTN) and basigin were identified as previously unrecognized obligatory subunits of PMCAs that dramatically increase the efficiency of PMCA-mediated...

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Detalles Bibliográficos
Autores principales: Gong, Deshun, Chi, Ximin, Ren, Kang, Huang, Gaoxingyu, Zhou, Gewei, Yan, Nieng, Lei, Jianlin, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127144/
https://www.ncbi.nlm.nih.gov/pubmed/30190470
http://dx.doi.org/10.1038/s41467-018-06075-7