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Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing

Pulmonary fibrosis, characterized by excessive collagen deposition in the lungs, comprises a key and debilitating component of chronic lung diseases. Methods are lacking for the direct visualization of fibrillar collagen throughout the whole murine lung, a capability that would aid the understanding...

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Detalles Bibliográficos
Autores principales: Ochoa, Lorenzo F., Kholodnykh, Alexander, Villarreal, Paula, Tian, Bing, Pal, Rahul, Freiberg, Alexander N., Brasier, Allan R., Motamedi, Massoud, Vargas, Gracie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127188/
https://www.ncbi.nlm.nih.gov/pubmed/30190498
http://dx.doi.org/10.1038/s41598-018-31182-2