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Imaging of Murine Whole Lung Fibrosis by Large Scale 3D Microscopy aided by Tissue Optical Clearing
Pulmonary fibrosis, characterized by excessive collagen deposition in the lungs, comprises a key and debilitating component of chronic lung diseases. Methods are lacking for the direct visualization of fibrillar collagen throughout the whole murine lung, a capability that would aid the understanding...
Autores principales: | Ochoa, Lorenzo F., Kholodnykh, Alexander, Villarreal, Paula, Tian, Bing, Pal, Rahul, Freiberg, Alexander N., Brasier, Allan R., Motamedi, Massoud, Vargas, Gracie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127188/ https://www.ncbi.nlm.nih.gov/pubmed/30190498 http://dx.doi.org/10.1038/s41598-018-31182-2 |
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