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The quaternary structure of Thermus thermophilus aldehyde dehydrogenase is stabilized by an evolutionary distinct C-terminal arm extension

Aldehyde dehydrogenases (ALDH) form a superfamily of dimeric or tetrameric enzymes that catalyze the oxidation of a broad range of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H. Despite their varied polypeptide chain length and...

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Detalles Bibliográficos
Autores principales: Hayes, Kevin, Noor, Mohamed, Djeghader, Ahmed, Armshaw, Patricia, Pembroke, Tony, Tofail, Syed, Soulimane, Tewfik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127216/
https://www.ncbi.nlm.nih.gov/pubmed/30190503
http://dx.doi.org/10.1038/s41598-018-31724-8