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Utilization of rare codon-rich markers for screening amino acid overproducers

The translation of rare codons relies on their corresponding rare tRNAs, which could not be fully charged under amino acid starvation. Theoretically, disrupted or retarded translation caused by the lack of charged rare tRNAs can be partially restored by feeding or intracellular synthesis of the corr...

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Detalles Bibliográficos
Autores principales: Zheng, Bo, Ma, Xiaoyan, Wang, Ning, Ding, Tingting, Guo, Liwei, Zhang, Xiaorong, Yang, Yu, Li, Chun, Huo, Yi-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127279/
https://www.ncbi.nlm.nih.gov/pubmed/30190534
http://dx.doi.org/10.1038/s41467-018-05830-0