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Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice

Variants of the SH3 and multiple ankyrin repeat domain 3 (SHANK3) gene, encoding excitatory postsynaptic core scaffolding proteins, are causally associated with numerous neurodevelopmental and neuropsychiatric disorders, including autism spectrum disorder (ASD), bipolar disorder, intellectual disabi...

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Detalles Bibliográficos
Autores principales: Jin, Chunmei, Kang, Hyojin, Ryu, Jae Ryun, Kim, Shinhyun, Zhang, Yinhua, Lee, Yeunkum, Kim, Yoonhee, Han, Kihoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127286/
https://www.ncbi.nlm.nih.gov/pubmed/30233305
http://dx.doi.org/10.3389/fnmol.2018.00250