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Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice
Variants of the SH3 and multiple ankyrin repeat domain 3 (SHANK3) gene, encoding excitatory postsynaptic core scaffolding proteins, are causally associated with numerous neurodevelopmental and neuropsychiatric disorders, including autism spectrum disorder (ASD), bipolar disorder, intellectual disabi...
Autores principales: | Jin, Chunmei, Kang, Hyojin, Ryu, Jae Ryun, Kim, Shinhyun, Zhang, Yinhua, Lee, Yeunkum, Kim, Yoonhee, Han, Kihoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127286/ https://www.ncbi.nlm.nih.gov/pubmed/30233305 http://dx.doi.org/10.3389/fnmol.2018.00250 |
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