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Comparative metabolism of xenobiotic chemicals by cytochrome P450s in the nematode Caenorhabditis elegans
We investigated the metabolic capabilities of C. elegans using compounds whose metabolism has been well characterised in mammalian systems. We find that similar metabolites are produced in C. elegans as in mammals but that C. elegans is deficient in CYP1-like metabolism, as has been seen in other st...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127299/ https://www.ncbi.nlm.nih.gov/pubmed/30190484 http://dx.doi.org/10.1038/s41598-018-31215-w |