mGlu1 Receptors Monopolize the Synaptic Control of Cerebellar Purkinje Cells by Epigenetically Down-Regulating mGlu5 Receptors

In cerebellar Purkinje cells (PCs) type-1 metabotropic glutamate (mGlu1) receptors play a key role in motor learning and drive the refinement of synaptic innervation during postnatal development. The cognate mGlu5 receptor is absent in mature PCs and shows low expression levels in the adult cerebell...

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Detalles Bibliográficos
Autores principales: Notartomaso, Serena, Nakao, Harumi, Mascio, Giada, Scarselli, Pamela, Cannella, Milena, Zappulla, Cristina, Madonna, Michele, Motolese, Marta, Gradini, Roberto, Liberatore, Francesca, Zonta, Micaela, Carmignoto, Giorgio, Battaglia, Giuseppe, Bruno, Valeria, Watanabe, Masahiko, Aiba, Atsu, Nicoletti, Ferdinando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127335/
https://www.ncbi.nlm.nih.gov/pubmed/30190524
http://dx.doi.org/10.1038/s41598-018-31369-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127335/
https://www.ncbi.nlm.nih.gov/pubmed/30190524
http://dx.doi.org/10.1038/s41598-018-31369-7

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