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Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation
Emerging evidence has revealed that Nestin not only serves as a biomarker for multipotent stem cells, but also regulates cell proliferation and invasion in various tumors. However, the mechanistic contributions of Nestin to cancer pathogenesis are still unknown. In the present study, previously thou...
Autores principales: | , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127343/ https://www.ncbi.nlm.nih.gov/pubmed/30190500 http://dx.doi.org/10.1038/s41467-018-05808-y |