Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation

Emerging evidence has revealed that Nestin not only serves as a biomarker for multipotent stem cells, but also regulates cell proliferation and invasion in various tumors. However, the mechanistic contributions of Nestin to cancer pathogenesis are still unknown. In the present study, previously thou...

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Detalles Bibliográficos
Autores principales: Zhang, Yanan, Wang, Jiancheng, Huang, Weijun, Cai, Jianye, Ba, Junhui, Wang, Yi, Ke, Qiong, Huang, Yinong, Liu, Xin, Qiu, Yuan, Lu, Qiying, Sui, Xin, Shi, Yue, Wang, Tao, Shen, Huiyong, Guan, Yuanjun, Zhou, Ying, Chen, Yuan, Wang, Maosheng, Xiang, Andy Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127343/
https://www.ncbi.nlm.nih.gov/pubmed/30190500
http://dx.doi.org/10.1038/s41467-018-05808-y

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