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Longitudinal Measurements of Intra- and Extracellular pH Gradient in a Rat Model of Glioma

This study presents the first longitudinal measurement of the intracellular/extracellular pH gradient in a rat glioma model using noninvasive magnetic resonance imaging. The acid–base balance in the brain is tightly controlled by endogenous buffers. Tumors often express a positive pH gradient (pH(i)...

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Detalles Bibliográficos
Autores principales: Lim, Heeseung, Albatany, Mohammed, Martínez-Santiesteban, Francisco, Bartha, Robert, Scholl, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Grapho Publications, LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127347/
https://www.ncbi.nlm.nih.gov/pubmed/30206544
http://dx.doi.org/10.18383/j.tom.2018.00001