Development of a Novel Nonradioisotopic Assay and Cdc25B Overexpression Cell Lines for Use in Screening for Cdc25B Inhibitors

PURPOSE: The cyclin-dependent kinase 1 (Cdk1) and cyclin B complex performs important roles in the transition from the G2 to M phase in the cell cycle through removal of inhibitory phosphates on Cdk1, and Cdc25B, which is a dual-specific phosphatase, mediates these dephosphorylation events. However,...

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Detalles Bibliográficos
Autores principales: Ha, Gyong Sik, Lee, Chung Min, Kim, Chan-wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127434/
https://www.ncbi.nlm.nih.gov/pubmed/30187708
http://dx.doi.org/10.3349/ymj.2018.59.8.995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127434/
https://www.ncbi.nlm.nih.gov/pubmed/30187708
http://dx.doi.org/10.3349/ymj.2018.59.8.995

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