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Identification of Biologically Essential Nodes via Determinative Power in Logical Models of Cellular Processes

A variety of biological networks can be modeled as logical or Boolean networks. However, a simplification of the reality to binary states of the nodes does not ease the difficulty of analyzing the dynamics of large, complex networks, such as signal transduction networks, due to the exponential depen...

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Detalles Bibliográficos
Autores principales: Pentzien, Trevor, Puniya, Bhanwar L., Helikar, Tomáš, Matache, Mihaela T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127445/
https://www.ncbi.nlm.nih.gov/pubmed/30233390
http://dx.doi.org/10.3389/fphys.2018.01185