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Spatiomechanical Modulation of EphB4-Ephrin-B2 Signaling in Neural Stem Cell Differentiation

Interactions between EphB4 receptor tyrosine kinases and their membrane-bound ephrin-B2 ligands on apposed cells play a regulatory role in neural stem cell differentiation. With both receptor and ligand constrained to move within the membranes of their respective cells, this signaling system inevita...

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Detalles Bibliográficos
Autores principales: Dong, Meimei, Spelke, Dawn P., Lee, Young Kwang, Chung, Jean K., Yu, Cheng-Han, Schaffer, David V., Groves, Jay T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127455/
https://www.ncbi.nlm.nih.gov/pubmed/30075851
http://dx.doi.org/10.1016/j.bpj.2018.06.031