Mucosal Autoimmunity to Cell-Bound GP2 Isoforms Is a Sensitive Marker in PSC and Associated With the Clinical Phenotype

Introduction: Zymogen granule glycoprotein 2 (GP2) was demonstrated as first autoimmune mucosal target in primary sclerosing cholangitis (PSC) associated with disease severity. Autoantibodies to four GP2 isoforms (aGP2(1−4)) were found in patients with inflammatory bowel diseases but reactivity agai...

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Detalles Bibliográficos
Autores principales: Sowa, Mandy, Kolenda, Rafał, Baumgart, Daniel C., Pratschke, Johann, Papp, Maria, Tornai, Tamas, Suchanski, Jaroslaw, Bogdanos, Dimitrios P., Mytilinaiou, Maria G., Hammermann, Jutta, Laass, Martin W., Conrad, Karsten, Schramm, Christoph, Franke, Andre, Roggenbuck, Dirk, Schierack, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127632/
https://www.ncbi.nlm.nih.gov/pubmed/30233574
http://dx.doi.org/10.3389/fimmu.2018.01959

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127632/
https://www.ncbi.nlm.nih.gov/pubmed/30233574
http://dx.doi.org/10.3389/fimmu.2018.01959

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