N-Methyl-D-Aspartate Receptor Link to the MAP Kinase Pathway in Cortical and Hippocampal Neurons and Microglia Is Dependent on Calcium Sensors and Is Blocked by α-Synuclein, Tau, and Phospho-Tau in Non-transgenic and Transgenic APP(Sw,Ind) Mice

N-methyl-D-aspartate receptors (NMDARs) respond to glutamate to allow the influx of calcium ions and the signaling to the mitogen-activated protein kinase (MAPK) cascade. Both MAPK- and Ca(2+)-mediated events are important for both neurotransmission and neural cell function and fate. Using a heterol...

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Detalles Bibliográficos
Autores principales: Franco, Rafael, Aguinaga, David, Reyes, Irene, Canela, Enric I., Lillo, Jaume, Tarutani, Airi, Hasegawa, Masato, del Ser-Badia, Anna, del Rio, José A., Kreutz, Michael R., Saura, Carlos A., Navarro, Gemma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127644/
https://www.ncbi.nlm.nih.gov/pubmed/30233307
http://dx.doi.org/10.3389/fnmol.2018.00273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127644/
https://www.ncbi.nlm.nih.gov/pubmed/30233307
http://dx.doi.org/10.3389/fnmol.2018.00273

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