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p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulation

Pancreatic cancer is one of the most aggressive and lethal malignancies worldwide, with a very poor prognosis and a five-year survival rate less than 8%. This dismal outcome is largely due to delayed diagnosis, early distant dissemination and resistance to conventional chemo-therapies. Kras mutation...

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Detalles Bibliográficos
Autores principales: Wang, Kai, Baldwin, Graham S, Nikfarjam, Mehrdad, He, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127653/
https://www.ncbi.nlm.nih.gov/pubmed/30197477
http://dx.doi.org/10.3748/wjg.v24.i33.3709