Trichosanthes kirilowii lectin alleviates diabetic nephropathy by inhibiting the LOX1/NF-κB/caspase-9 signaling pathway

Trichosanthes kirilowii lectin (TKL) has been reported to exert hypoglycemic effects in alloxan-induced diabetic mice. However, there is no evidence showing that it helps to prevent diabetic nephropathy (DN). We used a high glucose (HG)-induced HK-2 cell model and a streptozocin (STZ)-induced Wistar...

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Detalles Bibliográficos
Autores principales: Lu, Jiandong, Peng, Jinting, Xiang, Min, He, Liangping, Wang, Dongcai, Xiong, Guoliang, Li, Shunmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127671/
https://www.ncbi.nlm.nih.gov/pubmed/30038056
http://dx.doi.org/10.1042/BSR20180071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127671/
https://www.ncbi.nlm.nih.gov/pubmed/30038056
http://dx.doi.org/10.1042/BSR20180071

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