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Modulated expression of the HIV-1 2LTR zinc finger efficiently interferes with the HIV integration process

Lentiviral vectors have emerged as the most efficient system to stably transfer and insert genes into cells. By adding a tetracycline (Tet)-inducible promoter, transgene expression delivered by a lentiviral vector can be expressed whenever needed and halted when necessary. Here we have constructed a...

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Detalles Bibliográficos
Autores principales: Moonmuang, Sutpirat, Saoin, Somphot, Chupradit, Koollawat, Sakkhachornphop, Supachai, Israsena, Nipan, Rungsiwiwut, Ruttachuk, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127673/
https://www.ncbi.nlm.nih.gov/pubmed/30068696
http://dx.doi.org/10.1042/BSR20181109