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Integrin signaling downregulates filopodia during muscle–tendon attachment

Cells need to sense their environment to ensure accurate targeting to specific destinations. This occurs in developing muscles, which need to attach to tendon cells before muscle contractions can begin. Elongating myotube tips form filopodia, which are presumed to have sensory roles, and are later s...

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Detalles Bibliográficos
Autores principales: Richier, Benjamin, Inoue, Yoshiko, Dobramysl, Ulrich, Friedlander, Jonathan, Brown, Nicholas H., Gallop, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127725/
https://www.ncbi.nlm.nih.gov/pubmed/30054384
http://dx.doi.org/10.1242/jcs.217133