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Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA

Amidinobenzimidazole derivatives connected to 1-aryl-substituted 1,2,3-triazole through phenoxymethylene linkers 7a–7e, 8a–8e, and 9a–9e were designed and synthesised with the aim of evaluating their anti-bacterial and anti-trypanosomal activities and DNA/RNA binding affinity. Results from anti-bact...

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Detalles Bibliográficos
Autores principales: Bistrović, Andrea, Krstulović, Luka, Stolić, Ivana, Drenjančević, Domagoj, Talapko, Jasminka, Taylor, Martin C., Kelly, John M., Bajić, Miroslav, Raić-Malić, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127852/
https://www.ncbi.nlm.nih.gov/pubmed/30165753
http://dx.doi.org/10.1080/14756366.2018.1484733