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EGFL7 enhances surface expression of integrin α(5)β(1) to promote angiogenesis in malignant brain tumors

Glioblastoma (GBM) is a typically lethal type of brain tumor with a median survival of 15 months postdiagnosis. This negative prognosis prompted the exploration of alternative treatment options. In particular, the reliance of GBM on angiogenesis triggered the development of anti‐VEGF (vascular endot...

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Detalles Bibliográficos
Autores principales: Dudvarski Stanković, Nevenka, Bicker, Frank, Keller, Stefanie, Jones, David TW, Harter, Patrick N, Kienzle, Arne, Gillmann, Clarissa, Arnold, Philipp, Golebiewska, Anna, Keunen, Olivier, Giese, Alf, von Deimling, Andreas, Bäuerle, Tobias, Niclou, Simone P, Mittelbronn, Michel, Ye, Weilan, Pfister, Stefan M, Schmidt, Mirko HH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127886/
https://www.ncbi.nlm.nih.gov/pubmed/30065025
http://dx.doi.org/10.15252/emmm.201708420