Human Alzheimer’s disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology

BACKGROUND: Alzheimer’s disease (AD) is a chronic neurodegenerative disease with pathological hallmarks including the formation of extracellular aggregates of amyloid-beta (Aβ) known as plaques and intracellular tau tangles. Coincident with the formation of Aβ plaques is recruitment and activation o...

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Detalles Bibliográficos
Autores principales: Rothman, Sarah M., Tanis, Keith Q., Gandhi, Pallavi, Malkov, Vladislav, Marcus, Jacob, Pearson, Michelle, Stevens, Richard, Gilliland, Jason, Ware, Christopher, Mahadomrongkul, Veeravan, O’Loughlin, Elaine, Zeballos, Gonzalo, Smith, Roger, Howell, Bonnie J., Klappenbach, Joel, Kennedy, Matthew, Mirescu, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127905/
https://www.ncbi.nlm.nih.gov/pubmed/30189875
http://dx.doi.org/10.1186/s12974-018-1265-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127905/
https://www.ncbi.nlm.nih.gov/pubmed/30189875
http://dx.doi.org/10.1186/s12974-018-1265-7

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