Effective normalization for copy number variation in Hi-C data

BACKGROUND: Normalization is essential to ensure accurate analysis and proper interpretation of sequencing data, and chromosome conformation capture data such as Hi-C have particular challenges. Although several methods have been proposed, the most widely used type of normalization of Hi-C data usua...

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Detalles Bibliográficos
Autores principales: Servant, Nicolas, Varoquaux, Nelle, Heard, Edith, Barillot, Emmanuel, Vert, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127909/
https://www.ncbi.nlm.nih.gov/pubmed/30189838
http://dx.doi.org/10.1186/s12859-018-2256-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127909/
https://www.ncbi.nlm.nih.gov/pubmed/30189838
http://dx.doi.org/10.1186/s12859-018-2256-5

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