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Effective normalization for copy number variation in Hi-C data
BACKGROUND: Normalization is essential to ensure accurate analysis and proper interpretation of sequencing data, and chromosome conformation capture data such as Hi-C have particular challenges. Although several methods have been proposed, the most widely used type of normalization of Hi-C data usua...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127909/ https://www.ncbi.nlm.nih.gov/pubmed/30189838 http://dx.doi.org/10.1186/s12859-018-2256-5 |