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An integrated strategy for identifying new targets and inferring the mechanism of action: taking rhein as an example

BACKGROUND: Target identification is necessary for the comprehensive inference of the mechanism of action of a compound. The application of computational methods to predict the targets of bioactive compounds saves cost and time in drug research and development. Therefore, we designed an integrated s...

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Detalles Bibliográficos
Autores principales: Sun, Hao, Shen, Yiting, Luo, Guangwen, Cai, Yuepiao, Xiang, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127921/
https://www.ncbi.nlm.nih.gov/pubmed/30189851
http://dx.doi.org/10.1186/s12859-018-2346-4