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Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers

BACKGROUND: In breast cancer (BC), deregulation of DNA methylation leads to aberrant expressions and functions of key regulatory genes. In our study, we investigated the relationship between the methylation profiles of genes associated with cancer invasivity and clinico-pathological parameters. In d...

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Detalles Bibliográficos
Autores principales: Kalinkova, Lenka, Zmetakova, Iveta, Smolkova, Bozena, Minarik, Gabriel, Sedlackova, Tatiana, Horvathova Kajabova, Viera, Cierna, Zuzana, Mego, Michal, Fridrichova, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127923/
https://www.ncbi.nlm.nih.gov/pubmed/30189837
http://dx.doi.org/10.1186/s12885-018-4783-x